hrp0084p2-489 | Hypo | ESPE2015

The Effectiveness of Sirolimus in a Newborn with Hyperinsulinaemic Hypoglycaemia

Haliloglu Belma , Tuzun Heybet , Flanagan Sarah , Kaya Avni , Celik Muhittin

Background: Hyperinsulinaemic Hypoglycaemia (HH) is a rare genetic disease and the treatment of HH in cases with unresponsiveness to medical therapy is subtotal pancreatectomy. In a recent study, the authors showed that sirolimus could be an alternative treatment in these patients. We aimed to evaluate the effectiveness of sirolimus in a newborn with HH.Case: A 10 day-old neonate presented with hyperinsulinaemic hypoglycaemia (glucose: 26 mg/dl, insulin:...